November is Alzheimer’s disease Awareness Month, so we present our articles discussing Alzheimer’s disease and related topics such as testosterone, mild cognitive impairment, dementia, memory loss, and Parkinson’s disease.
Alzheimer’s disease cases are on the rise and the numbers will keep rising, as populations in many countries continue to age. Although Alzheimer’s disease isn’t an inevitable part of aging, the older one get the greater their risk of developing this mental disorder is. Below you will learn about the risk factors associated with Alzheimer’s disease, the progression of Alzheimer’s, as well as other conditions that could be tied to Alzheimer’s disease.
In Alzheimer’s disease, higher testosterone levels may increase aggression and hallucination risk: Study
In Alzheimer’s disease, higher testosterone levels may increase aggression and hallucination risk. Although low testosterone has been linked to a higher risk of Alzheimer’s disease, once a patient has developed Alzheimer’s, high levels of testosterone have been associated with greater agitation and aggression.
Researcher Dr. James Hall said, “What we’re showing is that testosterone can have a negative impact on patients with Alzheimer’s disease. It may be crucial to consider the possible unintended consequences before a patient is placed on testosterone-replacement therapy.”
The study evaluated 87 men with mild to moderate Alzheimer’s disease. The researchers found that the likelihood of experiencing hallucinations was 5.5 times greater in men with higher testosterone levels, compared to men with lower levels. Continue reading…
Mild cognitive impairment (MCI) patients with anxiety face faster Alzheimer’s disease progression. The risk of Alzheimer’s disease in mild cognitive impairment patients with mild, moderate, and severe anxiety was found to increase by 33, 78, and 135 percent, respectively.
The researchers also found that mild cognitive impairment patients who reported anxiety at any time during the follow-up period of the study had greater rates of atrophy in the medial temporal lobe region, an essential part of the brain responsible for creating memories that is often affected in Alzheimer’s disease.
Anxiety as a symptom of the MCI progression to Alzheimer’s disease has never been isolated in research, and this is one of the first studies to explore the detrimental effects of anxiety in Alzheimer’s disease. Numerous studies explored the link between depression and Alzheimer’s disease progression. Continue reading…
Alzheimer’s disease, dementia progression and onset linked to chronic sleep disturbances, poor sleep quality
Alzheimer’s disease and dementia progression and onset are linked to chronic sleep disturbances. Study lead Domenico Praticò explained, “The big biological question that we tried to address in this study is whether sleep disturbance is a risk factor to develop Alzheimer’s or is it something that manifests with the disease.”
The researchers initially looked at longitudinal studies that showed that people who reported chronic sleep disturbances were more likely to develop Alzheimer’s disease.
The researchers used Alzheimer’s mice models in which the rodents developed memory problems within one year.
The eight-week study involved mice when they were six months old – analogous to human mid-40s. The mice in on group were on a schedule to receive 12 hours of light and 12 hours of darkness, while the second group received 20 hours of light and only four hours of darkness, which meant reduced amount of sleep. Continue reading…
In Alzheimer’s disease, memory loss and cognitive function may be improved with regular moderate exercise
In Alzheimer’s disease, memory loss and cognitive function may be improved with regular moderate exercise. Exercise is effective in Alzheimer’s disease because it improves the efficiency of memory-related brain activity.
The researchers uncovered the beneficial effects of exercise in seniors with mild cognitive impairment. Not only does exercise improve memory recall but it improves brain function, too, which was confirmed with functional neuroimaging.
Lead researcher Dr. J. Carson Smith said, “We found that after 12 weeks of being on a moderate exercise program, study participants improved their neural efficiency – basically they were using fewer neural resources to perform the same memory task. No study has shown that a drug can do what we showed is possible with exercise.” Continue reading…
Sleeping in the side position may help reduce the chances of developing Alzheimer’s, Parkinson’s disease
Getting a good night’s sleep is important if we want to be productive and happy. Our bodies have been telling us this for years and so have countless sleep studies. Now we’re learning that it’s not just the quality of sleep we get that is vital to our well-being, it’s also the sleep positions we choose.
According to the latest research, sleeping on our side – as opposed to our back or stomach – could be a healthier position for our brain. Sleeping on the side allows our brain to clear out waste while we are resting.
Researchers from Stony Brook University used an MRI to monitor what is called the brain’s glymphathic pathway. This is the system that takes waste out of our brains. The researchers discovered this system works best when people sleep on their sides. Neurologists say brain waste can include proteins that make up the plaque linked to Alzheimer’s disease. This means that sleeping style could be a factor in developing such neurological diseases. Continue reading…