Even One Night of Poor Sleep Can Hurt Your Health

sleep and alzheimerA new study has found that even one night of bad sleep is enough to impact your brain health — more specifically, increase your risk of Alzheimer’s disease. The researchers found that a night of bad sleep increases protein build-up in the brain, which is linked to Alzheimer’s disease.

A build-up of beta-amyloid protein is commonly seen in patients with Alzheimer’s disease, but doctors and researchers are still unsure as to how this protein build-up related to Alzheimer’s. For example, the protein may trigger Alzheimer’s disease or might appear after Alzheimer’s disease is diagnosed.


The researchers from the National Institutes of Health in Maryland found that one night of bad sleep was enough to have an effect on beta-amyloid protein build-up. They looked at 20 volunteers and used a radioactive tracer to determine protein build-up.

For one night, the participants had a restful night’s sleep, but on the following night, they were sleep deprived. The scans using the tracer found a greater build-up of beta-amyloid proteins on the night sleep was restricted by five hours in two regions of the brain — the hippocampus, responsible for memory, and the thalamus, responsible for relaying signals to the brain and regulating sleep.

Sleep is often hailed as an important part of good health because it’s a time where the body can be reset and revived. When we sleep, waste is cleared from our brains, which is a possible explanation as to why there is greater protein build-up when we sleep less.

Poor sleep linked with Alzheimer’s disease has been studied quite often. It’s considered an early warning sign for future Alzheimer’s disease.


David Reynolds of the Alzheimer’s Research UK charity explained, “There is growing evidence of a link between disrupted sleep and Alzheimer’s disease, but it is difficult to tease apart cause and effect to determine whether sleep problems might cause Alzheimer’s brain changes, or vice-versa.”

It’s important that you work on improving your sleep each and every night as a possible preventative measure for Alzheimer’s disease. And if you’re having a hard time sleeping and natural remedies aren’t working effectively, it may be time you speak to your doctor about the underlying cause.

Also read: Alzheimer’s disease can be predicted through circadian rhythm disruptions

Author Bio

Mohan Garikiparithi got his degree in medicine from Osmania University (University of Health Sciences). He practiced clinical medicine for over a decade before he shifted his focus to the field of health communications. During his active practice he served as the head of the Dept. of Microbiology in a diagnostic centre in India. On a three-year communications program in Germany, Mohan developed a keen interest in German Medicine (Homoeopathy), and other alternative systems of medicine. He now advocates treating different medical conditions without the use of traditional drugs. An ardent squash player, Mohan believes in the importance of fitness and wellness.



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