Gallstone complications: Cholecystitis, cholangitis, gallbladder cancer, gangrene, and pancreatitis

Gallstones complications: Cholecystitis, cholangitis, gallbladder cancer, gangrene, and pancreatitisIf gallstones are not properly treated, they can lead to complications including cholecystitis, cholangitis, gallbladder cancer, gangrene, and pancreatitis. Gallstones are solid crystalized deposits that form from cholesterol and bile pigments in the gallbladder. There are two types of gallstones: cholesterol gallstones and pigment gallstones. Cholesterol gallstones account for 80 percent of gallstones and are usually yellow-green in color. Small and dark, pigment gallstones are made up of bilirubin.

Gallstones affect approximately 20 percent of women over 40 and eight percent of men. They can contribute to infection, which needs to be treated with antibiotics, but natural treatments can be effective in managing gallstones, too.
Below you will find the common complications which can arise in untreated or mistreated gallstones.

Complications of gallstones


Cholecystitis: This is inflammation of the gallbladder that can be caused by a bile duct blockage. It may begin as an episode of biliary colic and progress into cholecystitis. Constant pain will be experienced in the upper right area of the abdomen.

Cholangitis: Bile becomes infected, and the infection starts spreading through the intestines. Patients will become very sick with a high fever and an elevated white blood cell count.

Gangrene: Blood supply to the gallbladder is cut off, causes the organ to die off. This can also lead to the gallbladder rupturing, which can cause the infection to spread elsewhere in the body.

Jaundice: Skin and eyes begin to appear yellowish as a result of a bilirubin build-up. Jaundice occurs after a prolonged obstruction of the bile ducts.

Pancreatitis: This is inflammation of the pancreas that can be caused either by alcohol or gallstones. If gallstones obstruct the drainage duct, it can lead to inflammation thus contributing to pancreatitis.

Sepsis: Bacteria enter the blood and spread throughout the body. If the bacteria enter surrounding tissue, abscesses can form.

Fistula: This is an abnormal tract through which fluid can flow between hallow organs, or between an abscess and a hallow organ.

Gallstone ileus: This is an obstruction to the flow of gas, food, and liquid within the intestine either due to a mechanical obstruction or a functional obstruction.


Cancer of the gallbladder: It is unclear if gallstones cause cancer or if cancer causes gallstones. Gallbladder cancer as a result of gallstones occurs in less than one percent of patients.

Tips to manage gallstone complications

In order to reduce your risk of gallstone complications, don’t skip meals, gradually lose weight, and maintain a healthy weight. Being overweight or obese is a risk factor for gallstones.

Some natural remedies you can try to relieve gallstones include:

  • Drink apple cider vinegar diluted in water or apple juice to help relieve pain brought on by an attack. Apple cider vinegar also reduces cholesterol produced by the liver.
  • Drink lemon juice.
  • Drink vegetable juice – not the premixed cocktail versions, but pure juice from vegetables.
  • Increase fiber intake.
  • Rub castor oil over your abdomen, especially where your gallbladder is located.
  • Drink pear juice or consume pears.
  • Drink moderate amounts of wine.
  • Cut down on fatty foods.

Author Bio

Emily Lunardo studied medical sociology at York University with a strong focus on the social determinants of health and mental illness. She is a registered Zumba instructor, as well as a Canfit Pro trainer, who teaches fitness classes on a weekly basis. Emily practices healthy habits in her own life as well as helps others with their own personal health goals. Emily joined Bel Marra Health as a health writer in 2013.


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