New Study Sheds Light on Those with Highest Risk for Breakthrough COVID Infection

Global Virus variant and mutating cells concept or new coronavirus b.1.1.7 variants outbreak and covid-19 viral cell mutation as an influenza background with dangerous flu strain as a medical health risk as a 3D render.“Breakthrough” infections have become as big of a health concern as it is a buzzword. A new study, however, has highlighted who has the highest risk of infection despite vaccination.

Breakthrough COVID infections are defined as infections that occur even after a person has been fully vaccinated. No vaccine is entirely effective at eliminating infection risk; however, they are very effective at minimizing illness severity if an infection does occur.


Although relatively rare, breakthrough infections can happen. Even rarer is that a breakthrough infection will result in hospitalization or death.

A new study from British researchers looked at data from nearly 7 million vaccinated adults and identified who is at greatest risk of severe breakthrough infection. Of the 7 million, 5 million had received both doses of a COVID-19 vaccine.

They learned, perhaps unsurprisingly, that immunocompromised individuals were at the highest risk for breakthrough infections. Chemotherapy patients, those who had recently received a bone marrow or solid organ transplant, or had HIV/AIDS had the highest risk.

Along with those groups, people in nursing homes, with neurological disorders, or other chronic illnesses, had higher risk than the general population.

All in all, however, the data revealed that there are relatively few COVID-19 related hospitalizations that occur in people who’ve received both doses of vaccine.


Some health agencies around the world are exploring the idea of booster shots for immunocompromised individuals, which may reduce the risk of breakthrough infections in these populations.

It’s essential to assess your own risk when making decisions about how to behave during the pandemic. It may offer some relief to those remaining anxious about their risk after receiving vaccines, while it may lead others to exercise greater caution.

As always, follow local health protocols and continue to be diligent to reduce the risk of infection.

Author Bio

About eight years ago, Mat Lecompte had an epiphany. He’d been ignoring his health and suddenly realized he needed to do something about it. Since then, through hard work, determination and plenty of education, he has transformed his life. He’s changed his body composition by learning the ins and outs of nutrition, exercise, and fitness and wants to share his knowledge with you. Starting as a journalist over 10 years ago, Mat has not only honed his belief system and approach with practical experience, but he has also worked closely with nutritionists, dieticians, athletes, and fitness professionals. He embraces natural healing methods and believes that diet, exercise and willpower are the foundation of a healthy, happy, and drug-free existence.