Low Blood Pressure during Surgery Linked to Increased Risk for Postoperative Delirium

surgeon discusses a treatment with senior patientAccording to a new study presented at the ANESTHESIOLOGY 2021 annual meeting, patients who experience low blood pressure during surgery are at risk for postoperative delirium.

Postoperative delirium is a change in mental function that can cause confusion after surgery. It’s the most common surgical complication for older adults and it can be caused by various factors, including insomnia, anxiety, pain, and stress.


The study included 316,717 patients who had noncardiac surgery at one of two hospitals between 2005 and 2017. Of the patients, 2,183 were diagnosed with delirium within 30 days after surgery. It was noted that of those patients, 41.7% had an average systolic and diastolic blood pressure below 55mgHg during the surgery for fewer than 15 minutes. Out of these patients, 2.6% had it for longer than 15 minutes.

It was concluded that patients who experienced low blood pressure were up to 60% more likely to experience postoperative delirium. The effects were found to be magnified in patients who had longer surgeries.

Postoperative Delirium In the Elderly

Postoperative delirium can affect anyone, but elderly patients have been found to be at the highest risk. It can typically last one to three days after surgery, but some patients may experience long-term memory loss, difficulty learning, thinking, and concentrating.

The senior author of the study Dr. Eikermann said, “Physician anesthesiologists measure patients’ blood pressure at least every three minutes during surgery. The study shows they can help decrease the risk of postoperative delirium by immediately providing medication to increase blood pressure when it falls.”

Postoperative delirium is a condition that can be a major obstacle to a quick recovery from surgery. It can lead to patients having to be more dependent on others for daily living. Researchers also believe that it could lead to an accelerated cognitive decline.

This study helps to show that rapidly addressing low blood pressure during surgery could prevent delirium and help with recovery. Physicians must understand the relationship between blood pressure during surgery and delirium experienced afterward.


While previous small studies have been inconclusive, this new study has been able to outline the link between mental health and low blood pressure. It’s believed that low blood pressure decreases the supply of oxygen and glucose to the brain, causing delirium and other cognitive issues in the future.

More studies are needed to add to the evidence found by these researchers. Patients who have experienced long-term cognitive effects after surgery may have suffered a drop in blood pressure during their operation.

The next step is to find how to reduce the effects of low blood pressure during surgery and inform the anesthesiologist about the importance of providing medication to increase blood pressure when it falls during surgery.

Author Bio

Sarah began her interest in nutritional healing at an early age. After going through health problems and becoming frustrated with the conventional ways doctors wanted to treat her illness (which were not working), she took it upon herself to find alternative treatments. This led her to revolutionize her own diet to help her get healthier and tackle her health problems. She began treating her illness by living a more balanced lifestyle through healthy food choices, exercise and other alternative medicine such as meditation. This total positive lifestyle change led her to earn a diploma in Nutritional Therapy from Health Sciences Academy in London, England. Today, Sarah enjoys helping others by teaching healthy lifestyle changes through her personal consultations and with her regular contributions to the Doctors Health Press. Also, passionate about following her dreams in life, Sarah moved to France and lived in Paris for over 5 years where she earned a certification in beadwork and embroidery from Lesage (an atelier owned by Chanel). She then went on to be a familiar face sitting front row and reporting from Paris Fashion Week. Sarah continues to practice some of the cultural ways of life she learned while in Europe. They enjoy their food, and take the time to relax and enjoy many of life’s little moments. These are life lessons she is glad to have brought back home with her.