Hypertension May Be Linked to Significant Bone Aging: Study

Senior African American Male Measuring Arterial Blood Pressure Having Hypertension Symptom Sitting On Couch At Home. High Blood-Pressure, Health Problem ConceptIt’s been known for a while that high blood pressure (hypertension) is linked to a greater risk of heart disease and stroke, but new research suggests it may also be connected to significant bone aging. The study, presented at the American Heart Association’s Hypertension Scientific Sessions 2022 conference, found that people with hypertension were more likely to have bone mineral density declines and fractures than those without the condition.

High blood pressure and osteoporosis are both conditions that are prevalent among older people. Since many people have hypertension and osteoporosis simultaneously, researchers used mice to find how the two conditions may be associated.


Lead study author Elizabeth Maria Hennen said, “By understanding how hypertension contributes to osteoporosis, we may be able to reduce the risk of osteoporosis and better protect people later in life from having fragility fractures and a lower quality of life.”

The Study

For the study, researchers used young mice with induced hypertension and compared them to older mice without hypertension to assess the potential relationship to bone aging. All mice were examined for six weeks, and micro-computed tomography, an advanced imaging technique, was used to analyze their bones. Bone health was determined by the density and strength of the bone, and mathematical algorithms were used to estimate the effects of hypertension on the bones.

It was found that the young mice with induced hypertension had a significant 24% reduction in bone volume fraction. They also had an 18% reduction in the thickness of the sponge-like trabecular bone located at the end of long bones and a 34% reduction in estimated failure force, which is the ability of bones to withstand different types of force.

Inflammation also seemed to play a role in bone health. Researchers found that the mice with poor bone health had a continued state of inflammation.

“In these mice, being hypertensive at a younger age essentially aged bones as if they were 15-25 human years older,” Hennen said.


As more research becomes available, doctors can help prevent osteoporosis and other conditions more easily. This study shows how hypertension can be marked as a possible risk factor for osteoporosis. So, for younger people with high blood pressure, steps should be taken to get it under control before it leads to osteoporosis later in life.

Maintaining healthy blood pressure can help reduce the risk of osteoporosis, heart disease, stroke and other conditions. Healthy Blood Pressure Support has been shown in human clinical studies to help support healthy blood pressure making it an excellent choice for those looking to reduce their risk of hypertension. In addition, Healthy Blood Pressure Support also promotes healthy cholesterol levels and cardiovascular health.

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Author Bio

Sarah began her interest in nutritional healing at an early age. After going through health problems and becoming frustrated with the conventional ways doctors wanted to treat her illness (which were not working), she took it upon herself to find alternative treatments. This led her to revolutionize her own diet to help her get healthier and tackle her health problems. She began treating her illness by living a more balanced lifestyle through healthy food choices, exercise and other alternative medicine such as meditation. This total positive lifestyle change led her to earn a diploma in Nutritional Therapy from Health Sciences Academy in London, England. Today, Sarah enjoys helping others by teaching healthy lifestyle changes through her personal consultations and with her regular contributions to the Doctors Health Press. Also, passionate about following her dreams in life, Sarah moved to France and lived in Paris for over 5 years where she earned a certification in beadwork and embroidery from Lesage (an atelier owned by Chanel). She then went on to be a familiar face sitting front row and reporting from Paris Fashion Week. Sarah continues to practice some of the cultural ways of life she learned while in Europe. They enjoy their food, and take the time to relax and enjoy many of life’s little moments. These are life lessons she is glad to have brought back home with her.