Adults With High Stress Hormones Were More Likely To Develop High Blood Pressure & Heart Events

A person suffering from depressionAdults who have high-stress hormones are more likely to develop high blood pressure and heart events compared to those who have lower stress hormones. This new research was published in the American Heart Association journal, Hypertension.

Previous studies have found that cumulative exposure to long-term or traumatic stress can increase cardiovascular risk, and there is growing evidence to suggest a mind-heart-body connection.


This relationship indicates a person’s mind can positively or negatively affect cardiovascular health, cardiovascular risk factors, and risk for cardiovascular disease events over time. However, these studies only focused on patients with pre-existing hypertension. Studies looking at adults without hypertension were lacking.

“Previous research focused on the relationship between stress hormone levels and hypertension or cardiovascular events in patients with existing hypertension. However, studies looking at adults without high blood pressure were lacking. It is important to examine the impact of stress on adults in the general population because it provides new information about whether routine measurement of stress hormones needs to be considered to prevent hypertension and CVD events,” said study author Kosuke Inoue, M.D., Ph.D.

The Development of Cardiovascular Events

For this new study, more than 6,000 men and women from six U.S. communities were followed from September 2005 to June 2018 and monitored for the development of hypertension and cardiovascular events such as heart attack, stroke, or chest pain. Researchers also analyzed levels of norepinephrine, epinephrine, dopamine, and cortisol.

“Although all of these hormones are produced in the adrenal gland, they have different roles and mechanisms to influence the cardiovascular system, so it is important to study their relationship with hypertension and cardiovascular events, individually,” Inoue said.


The analysis of the stress hormones and the risk of cardiovascular events found that over a median of 6.5 years, every time the levels of the four stress hormones doubled, there was a 21-31% increase in the risk of developing hypertension.

During the median of 11.2 years, there was a 90% increased risk of cardiovascular events with each doubling of cortisol levels. There was no association found between catecholamines and cardiovascular events.

Inoue and his team found it to be a challenge to study psychosocial stress since it is personal, and its impact varies for each individual. They believe the following key research question is whether increased testing of stress hormones in patients could be helpful in preventing hypertension and cardiovascular events.

Author Bio

Sarah began her interest in nutritional healing at an early age. After going through health problems and becoming frustrated with the conventional ways doctors wanted to treat her illness (which were not working), she took it upon herself to find alternative treatments. This led her to revolutionize her own diet to help her get healthier and tackle her health problems. She began treating her illness by living a more balanced lifestyle through healthy food choices, exercise and other alternative medicine such as meditation. This total positive lifestyle change led her to earn a diploma in Nutritional Therapy from Health Sciences Academy in London, England. Today, Sarah enjoys helping others by teaching healthy lifestyle changes through her personal consultations and with her regular contributions to the Doctors Health Press. Also, passionate about following her dreams in life, Sarah moved to France and lived in Paris for over 5 years where she earned a certification in beadwork and embroidery from Lesage (an atelier owned by Chanel). She then went on to be a familiar face sitting front row and reporting from Paris Fashion Week. Sarah continues to practice some of the cultural ways of life she learned while in Europe. They enjoy their food, and take the time to relax and enjoy many of life’s little moments. These are life lessons she is glad to have brought back home with her.


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