Five new genes that play a role in colon cancer have been discovered. The findings come from a study of over 1,000 people with colon cancer. The five genes uncovered are considered very rare, so additional research is required to confirm their association and link to colon cancer.
Study leader Richard Houlston said, “Our study is the largest ever conducted of the genetics of bowel [colon] cancer, and sets out a detailed map of the disease that could lead us to new ways of treating or preventing. The research closes one chapter in the study of bowel cancer by concluding that all the major risk genes have now been found. But it opens another by underlining the importance of tracking down the many missing genetic variations, which each have a very small effect alone, but together make the biggest impact on inherited risk.”
The findings were published in the journal Nature Communications.