Anemia medications don’t improve kidney patients’ well-being

anemiaKidney patients are often given anemia medication, but new findings suggest that it may do very little to improve their well-being. The anemia drugs are called erythropoietin-stimulating agents (ESAs), and the findings work to back up the current implemented guidelines on using ESAs.

Senior researcher Dr. Navdeep Tangri said, patients may still benefit from the medications as they reduce the need for blood transfusions, but added, “This should close the book on the idea that these drugs help with exhaustion and improve patients’ quality of life.”


Anemia is common in chronic kidney disease, and so ESAs are normally prescribed to help treat anemia. Other findings suggested that raising hemoglobin beyond a certain level with ESAs resulted in an increased risk of heart attack, stroke, and blood clots.

The study reviewed 17 clinical trials with results reaffirming the current knowledge of the dangers surrounding ESAs. Researchers believe that overall well-being does not improve, because oftentimes patients are older, live a sedentary lifestyle, and have other medical conditions aside from chronic kidney disease.

When patients are younger and more active, ESAs are found to help overall well-being. Raising hemoglobin levels beyond nine in these patients does show benefits.
The review of clinical trials showed that raising hemoglobin levels did not boost quality of life for kidney disease patients. In some patients who were not on dialysis, certain improvements due to raised hemoglobin were seen, but Dr. Tangri did not find them to be medically significant.

The findings were published in the Annals of Internal Medicine.


Author Bio

Mohan Garikiparithi got his degree in medicine from Osmania University (University of Health Sciences). He practiced clinical medicine for over a decade before he shifted his focus to the field of health communications. During his active practice he served as the head of the Dept. of Microbiology in a diagnostic centre in India. On a three-year communications program in Germany, Mohan developed a keen interest in German Medicine (Homoeopathy), and other alternative systems of medicine. He now advocates treating different medical conditions without the use of traditional drugs. An ardent squash player, Mohan believes in the importance of fitness and wellness.