A new study is offering up a new method to properly diagnose nocturnal polyuria. Researcher Jeffrey P. Weiss explained, “You should do a 24-hour voiding diary in addition to medication history and examination in order to diagnose polyuria.”
Nocturnal polyuria is diagnosed if urine volume is excess 33 percent within 24 hours for individuals over 64 years. Nocturnal polyuria is also defined as urine output exceeding 90 mL/hr without a 24-hour reference.
The researchers analyzed the data of 524 patients who completed a 24-hour flow volume while being monitored for lower urinary tract symptoms. The researchers reviewed past medical history, surgical history, along with eight groups of medications.
They measured the rate of overactive bladder, benign prostatic hyperplasia (BPH), urethral stricture, urinary incontinence, hypertension, hypothyroidism, diabetes, urethral obstruction, prostate cancer, pedal enema, neurogenic bladder, Parkinson’s disease, and sleep apnea.
Some risk factors were found to be overrepresented among this population compared to the general population, such as overactive bladder and BPH, while others were underrepresented.
Patients were divided into two groups: 145 patients with nocturnal polyuria and 379 with normal urinary output.
Between the two groups, there were no statistical differences between risk factors, but the researchers were surprised that sleep apnea and pedal enema did not correlate with nocturnal polyuria.
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