Osteoarthritis Patients Are at an Increased Risk of Cardiovascular Disease Death: Study

Reviewed by Dr. Victor Marchione, MD.
Written by Mat Lecompte
Published on

osteoarthritis cardiovascular deathFor those who have a diagnosis of osteoarthritis, research now shows that there may be a higher risk of dying from cardiovascular disease. A study performed at Lund University in Sweden has found a link between osteoarthritis and mortality that outlines the importance of cardiovascular disease prevention.

It was shown that the risk of dying from cardiovascular disease was higher for people with osteoarthritis than for the rest of the population. This new epidemiological study looked at approximately 469,000 people living in Skåne, Sweden who were followed for just over ten years starting in 2003. Each participant was between the age of 45 and 84 years.

The group included 16,000 patients with knee arthritis, 4,000 with wrist arthritis, 9,000 with hip arthritis, and 5,500 with other forms of osteoarthritis. They had all been previously diagnosed before the study began in 2003.

Martin Englund, professor at Lund University and physician at Skåne University Hospital, spoke about the research. “We looked at the cause of death for those who died between 2004 and 2014 and who had previously been diagnosed with osteoarthritis and compared the results with the rest of the population in the same region. The groups were not different in terms of most causes of death, but we saw the risk of mortality from cardiovascular disease was higher for those with an osteoarthritis diagnosis. The risk did not increase in the short term after the osteoarthritis diagnosis, but the longer a person had had osteoarthritis, the higher the risk of mortality from cardiovascular diseases compared with the background population, e.g. if a person had a knee arthritis diagnosis for 9 to 11 years, the risk was 16 per cent higher.”

Risk Prevention

This study outlined the importance of cardiovascular disease prevention in those with osteoarthritis. The findings did uncover some shocking statistics showing that for every 100,000 inhabitants who have had osteoarthritis for 9–11 years, 40 or more die of cardiovascular disease per year. This was compared to the population without osteoarthritis in corresponding age and gender.

Although these findings were made, the mechanisms behind cardiovascular disease and osteoarthritis were not fully investigated, and therefore the causal link is not yet fully known. Author lead Martin Englund did have a theory, saying, “Osteoarthritis causes pain, which often results in people not being as mobile and becoming sedentary instead. Thus, there is a risk of weight gain, which we know leads to secondary diseases, including cardiovascular diseases. There are also other background factors in common for osteoarthritis and cardiovascular disease. Inflammation can be a contributory cause of osteoarthritis and can also lead to an increased risk of cardiovascular disease. Regardless, it’s important to be physically active and keep body weight in check. In many countries there are special education programs for those suffering from osteoarthritis where you can get information on the disease as well as help and exercise advice.”


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On any matter relating to your health or well-being, please check with an appropriate health professional. No statement herein is to be construed as a diagnosis, treatment, preventative, or cure for any disease, disorder or abnormal physical state. The statements herein have not been evaluated by the Foods and Drugs Administration or Health Canada. Dr. Marchione and the doctors on the Bel Marra Health Editorial Team are compensated by Bel Marra Health for their work in creating content, consulting along with formulating and endorsing products.

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