High Blood Pressure at Any Age Accelerate a Decline in Cognitive Performance

Reviewed by Dr. Victor Marchione, MD.
Written by Mat Lecompte
Published on

Senior man using medical device to measure blood pressureNew research has found that high blood pressure may accelerate cognitive decline in middle-aged and older adults. Studies such as this are becoming imperative since nearly half of American adults have high blood pressure or hypertension.

According to the study published in Hypertension, high blood pressure is a risk factor for cognitive decline. This includes such symptoms as memory, verbal fluency, concentration, and attention. Systolic blood pressure of 120 mmHg or higher and 80 mmHg diastolic is considered elevated.

“We initially anticipated that the negative effects of hypertension on cognitive function would be more critical when hypertension started at a younger age. However, our results show similar accelerated cognitive performance decline whether hypertension started in middle age or at older ages,” said study author Sandhi M. Barreto, M.D. “We also found that effectively treating high blood pressure at any age in adulthood could reduce or prevent this acceleration. Collectively, the findings suggest hypertension needs to be prevented, diagnosed, and effectively treated in adults of any age to preserve cognitive function.”

The study analyzed findings from existing research that included cognitive health and blood pressure information from more than 7,000 adults in Brazil, whose average age was about 59 years old at the start of the study. Each participant was followed for an average of nearly four years. The participants’ cognitive testing included analysis of memory, verbal fluency, and executive function, which includes concentration, attention, and other factors.

It was found that systolic blood pressure between 121 and 139 mmHg or diastolic blood pressure between 81 and 89 mmHg with no antihypertensive medication use was associated with accelerated cognitive performance decline among middle-aged and older individuals. The speed of decline in cognition was found to happen regardless of the duration of hypertension.

Researchers also noted that adults with uncontrolled hypertension tended to experience notably faster declines in memory and global cognitive function than adults who had controlled hypertension.

The Importance of Blood Pressure Control

This study helps to outline the importance of blood pressure control. It highlights the importance of diagnosing and controlling hypertension in patients of any age to prevent or slow down cognitive decline. As the study shows, there is a need to maintain lower blood pressure levels throughout life since even prehypertension levels were associated with cognitive decline.

Further research is needed to confirm some of the study’s findings as there were some limitations, including a relatively short follow-up period and the self-reporting of hypertension at baseline. All participants in the study were from Brazil. However, researchers believe that these findings apply to other regions.


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On any matter relating to your health or well-being, please check with an appropriate health professional. No statement herein is to be construed as a diagnosis, treatment, preventative, or cure for any disease, disorder or abnormal physical state. The statements herein have not been evaluated by the Foods and Drugs Administration or Health Canada. Dr. Marchione and the doctors on the Bel Marra Health Editorial Team are compensated by Bel Marra Health for their work in creating content, consulting along with formulating and endorsing products.

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