Pain perception altered in Alzheimer’s disease

Written by Mohan Garikiparithi
Published on

Pain perception altered in Alzheimer’s diseasePain perception has been found to be altered in patients with Alzheimer’s disease. The study found that Alzheimer’s disease may change a person’s ability to experience pain or recognize that they are in pain. This is problematic because the concomitant health issues may go undetected, causing further complications.

In the study that carried on for three years, researchers tested two groups of adults over the age of 65. One group consisted of Alzheimer’s disease patients and the second – control – group did not have Alzheimer’s disease.

The participants were subjected to different heat sensations and then were asked to report their pain levels.

First author Todd Monroe said, “We found that participants with Alzheimer’s disease required higher temperatures to report sensing warmth, mild pain, and moderate pain than the other participants. What we didn’t find was a difference between the two groups in reporting how unpleasant the sensations were at any level.”
The subjects in the Alzheimer’s group were less likely to recognize pain.

Monroe added, “While we found that their ability to detect pain was reduced, we found no evidence that people with Alzheimer’s disease are less distressed by pain nor that pain becomes less unpleasant as their disease worsens.”

Additional research is required to further explore pain perception among Alzheimer’s patients. The researchers recommend that physicians use a variety of tests to assess pain sensitivity in their patients – especially in those who have problems with verbal communication.

Monroe concluded, “As people age, the risk of developing pain increases, and as the population of older adults continues to grow, so will the number of people diagnosed with Alzheimer’s disease. We need to find ways to improve pain care in people with all forms of dementia and help alleviate unnecessary suffering in this highly vulnerable population.”

Also, read Bel Marra Health’s article: MIND diet reduces Alzheimer’s disease risk by 53 percent.


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On any matter relating to your health or well-being, please check with an appropriate health professional. No statement herein is to be construed as a diagnosis, treatment, preventative, or cure for any disease, disorder or abnormal physical state. The statements herein have not been evaluated by the Foods and Drugs Administration or Health Canada. Dr. Marchione and the doctors on the Bel Marra Health Editorial Team are compensated by Bel Marra Health for their work in creating content, consulting along with formulating and endorsing products.

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