Psoriasis is a chronic kidney disease (CKD) risk factor independent of diabetes and heart disease: Study

By: Emily Lunardo | Skin Health | Tuesday, February 16, 2016 - 12:30 PM

PsoriasisPsoriasis is a risk factor for chronic kidney disease (CKD), and it’s found to be independent of diabetes and heart disease, which are other known risk factors for CKD. The researchers recommend close monitoring of kidney problems in kidney patients who have three percent or more of their body affected by psoriasis, a skin condition. Detecting kidney problem early on and beginning treatment right away can prevent it from developing into chronic kidney disease.

Psoriasis affects the skin and the joints, and is prevalent in two to four percent of the general population. Other research has shown links between psoriasis and diabetes and heart disease, while studies on psoriasis and kidney disease have been small and offered conflicting results.

A research team from Philadelphia decided to compare the risk of chronic kidney disease in patients with and without psoriasis.

The researchers identified 143,883 patients with psoriasis who were matched with 689,702 controls. The team then analyzed patients who had a diagnosis of CKD based on tests between 2003 and 2010.

Researchers found that patients with psoriasis, especially with severe psoriasis, were at a higher risk of developing later stage kidney disease, compared to the control patients. Even after adjusting for other known risk factors, psoriasis remained an independent risk factor for chronic kidney disease.

The researchers concluded, “Future studies are warranted to confirm our findings, determine the mechanisms mediating renal insufficiency in psoriasis, and examine the impact of treatment for psoriasis on the risk of chronic kidney disease.”

Psoriasis treatment and home remedies

There is no cure for psoriasis, but treatment options are available, aiming to stop skin cells from producing quickly in order to reduce inflammation and plaque formation, as well as to remove scales and smooth the skin, commonly done through topical treatments.

Topical treatments for psoriasis include topical corticosteroids, which work as a powerful anti-inflammatory. Although topical corticosteroids are an effective mode of treatment, they can cause thinning of the skin over time and as well as resistance to treatment. To reduce ineffectiveness and resistance to corticosteroids, it’s best to use this form of treatment during severe flare-ups.

Other topical treatments include vitamin D analogues, anthralin which is believed to normalize skin DNA activity, topical retinoids, calcineurin inhibitors, salicylic acid, coal tar, and moisturizers.

Aside from topical treatment, light therapy has been shown to offer relief for psoriasis, too. Sunlight, UVB phototherapy, narrow band UVB therapy, Goeckerman therapy, photochemotherapy, and eximer laser are all different forms of light therapy used to treat psoriasis.

Lastly, oral and injected medications are often used when a patient is resistant to other forms of treatment, but typically are administered for a short period of time and are often alternated with other forms of treatment as well.

Lifestyle and home remedies to treat psoriasis include:

  • Taking daily baths
  • Using moisturizer
  • Exposing skin to small amounts of sunlight
  • Avoiding psoriasis triggers, which can be stress, smoking, intense sun exposure, etc.
  • Avoiding alcohol consumption.

Working with your doctor can help determine the best treatment plan for you. Furthermore, your doctor should closely monitor your kidney function as well in order to prevent any complications.


Related Reading:

Psoriasis skin disorder inflames arteries, increases heart disease risk

New research suggests psoriasis, a skin disorder, leads to artery inflammation and increases heart disease risk. Senior investigator Dr. Nehal Mehta said, “As the amount of psoriasis increases, the amount of blood vessel inflammation increases.” The team also uncovered that psoriasis may add to the risk of stroke and heart attack, even mild cases. Continue reading…

Link between psoriasis and risk of depression: Study

The results of a recent study published online by JAMA Dermatology show that researchers were able to confirm the link between psoriasis, a chronic inflammatory skin condition, and an increased risk of depression. However, the risk was unrelated to the severity of psoriasis. Continue reading…


Source:
https://www.sciencedaily.com/releases/2013/10/131015191357.htm
http://www.mayoclinic.org/diseases-conditions/psoriasis/basics/treatment/con-20030838
http://www.mayoclinic.org/diseases-conditions/psoriasis/basics/lifestyle-home-remedies/con-20030838


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